Job Description

Requisition Number 06195
Department Name: Immunology and Microbiology - FL
Position Type: Full Time
Position Title Postdoctoral Associate - Solt Lab
Position Summary:

A NIH-funded postdoctoral position within the Department of Immunology and Microbiology at the Scripps Research Institute, Florida campus, is available to study REV-ERB-mediated transcriptional control of TH17-mediated autoimmunity and chronic inflammation. The candidate will use currently available strains of reporter and gene-deficient mice in combination with ROR- and REV-ERB-selective small molecules, that we have developed, to dissect the molecular mechanisms by which the REV-ERBs control TH17 cell function under normal and disease states. Building off of previously published work (PMID: 30590045), we aim to understand how ligands influence receptor activity and downstream transcriptional output, environmental factors that affect REV-ERB activity driving disease pathogenesis, and cross-talk between the REV-ERBs and other nuclear receptors.

This project is multidisciplinary, using a variety of techniques and approaches including immunology, mouse genetics, molecular biology techniques, chemical biology, and genomics. A successful candidate will contribute to all aspects of the project, including experimental design, analysis, and data interpretation. Experience with next-generation sequencing is preferred.

Position Description

A Postdoctoral Associate is a direct pay individual in a Division 3 status. Postdoctoral Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Postdoctoral Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Postdoctoral Associates do not have consulting privileges.

Location: Florida
Additional Information:
Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

The ideal candidate will have a Ph.D. (or MD/PhD) in immunology, a solid background in molecular biology, and a strong publication record.

The ideal candidate should have extensive skills with flow cytometry, mouse genetics, animal models of inflammatory diseases, and experience with next generation sequencing - both execution and analysis of data.

The candidate will work in a fast-paced environment and should be self-motivated to work on challenging projects, detail oriented, and possess excellent organizational, written, and oral communication skills.

To apply, submit a CV, a brief description of research interests, experience, and contact information (email address and phone number) of three references to: lsolt@scripps.edu.

Preferred Qualifications:
Compensation:
Job Closing Date:
Open Until Filled Yes
Job Posting Category Postdoctoral
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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