|Department Name:||Chemistry - CA|
|Position Type:||Full Time|
|Position Title||Postdoctoral Associate|
|Position Summary:|| |
Scripps Research is seeking a Postdoctoral Associate for the Chemistry Department.
The project will test the hypothesis that pharmacologic activation of the ATF6 or XBPs arm of the Unfolded Protein Response stress-responsive signaling pathway will alter the kinetic stability of transthyretin (TTR), possibly by altering the packing of the F87 residue. We will study whether secretory proteostasis network pathways alter the structure and modify the aggregation propensity of TTR. We will also assess whether arm-selective unfolded protein response inhibition during stress reduces TTR kinetic stability enhancing amyloidogenicity.
|Position Description|| |
A Postdoctoral Associate is a direct pay individual in a Division 3 status. Postdoctoral Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Postdoctoral Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Postdoctoral Associates do not have consulting privileges.
|Physical Requirements:|| |
This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.
|Basic Qualifications:|| |
Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
|Job Closing Date:|
|Open Until Filled||Yes|
|Job Posting Category||Postdoctoral|
|EEO Statement|| |
The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.