Job Description

Requisition Number 07046
Department Name: Immunology and Microbiology - CA
Position Type: Full Time
Position Title Postdoctoral Associate
Position Summary:

Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, accounting for over half a million deaths per year. Chronic infections with hepatitis B (HBV) and C (HCV) viruses have been recognized as main human liver carcinogens. Multiple non-viral factors have also been implicated in the development of HCC. The development of non-alcoholic steatohepatitis (NASH) and liver fibrosis represent high risk factors for HCC. Remarkably, we recently found that cyclophilin inhibitors suppress the development of viral-induced and non-viral-induced liver fibrosis and HCC in mouse models. However, their mechanisms of action are totally unknown.
A postdoctoral position is immediately available to study the liver damage protective effects and mechanisms of action of cyclophilin inhibitors, both in vivo and in vitro, and to determine the potential of cyclophilin inhibitors as anti-liver damage drugs.

Position Description
Location: California
Additional Information:

Research Description: Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide, accounting for over half a million deaths per year. Chronic infections with hepatitis B (HBV) and C (HCV) viruses have been recognized as main human liver carcinogens. Multiple non-viral factors have also been implicated in the development of HCC. The development of non-alcoholic steatohepatitis (NASH) and liver fibrosis represent high risk factors for HCC. Remarkably, we recently found that cyclophilin inhibitors suppress the development of viral-induced and non-viral-induced liver fibrosis and HCC in mouse models. However, their mechanisms of action are totally unknown.

Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

Must possess a recent (less than one year) Ph.D. in immunology, virology, microbiology, or a relevant field from a credited university or institute. A pending doctoral degree (to be obtained in a few months) is also considered.

  • Have a good publishing record with first-author papers.
  • Minimum of two years of experience with mouse models and cell culture.
  • Experience with PCR, ELISA, Western blots, flow cytometry, and/or other molecular techniques.
  • Competent computer and analytical skills.
  • Fast learner, self-motivated, independent and hard worker, and diligent team member with great organization and communication/writing and time management skills.
Preferred Qualifications:

Prefer a recent doctoral degree. A pending doctoral degree is also considered with approval of the Principal Investigator.

Compensation: Salary is commensurate with experience.
Job Closing Date:
Open Until Filled Yes
Job Posting Category Postdoctoral
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

Please click on the link below to apply for this position. A new window will open and direct you to apply at our corporate careers page. We look forward to hearing from you!

Apply Online