Job Description

Requisition Number 06703
Department Name: Chemistry - CA
Position Type: Full Time
Position Title Postdoctoral Associate
Position Summary:

Ghadiri Laboratory at the Scripps Research, Department of Chemistry, and the Skaggs Institute for Chemical Biology is currently seeking talented Postdoctoral Fellow candidates with a strong background in biology, molecular biology, chemical biology, biochemistry, and/or bioinformatics.

Ghadiri and coworkers are developing novel methods for the directed remodeling of the gut microbiota in vitro and in vivo to probe the chemical biology of gut microbiome, identify new targets and pathways, and develop novel classes of therapeutics to prevent the onset or progression of chronic diseases such as atherosclerosis, diabetes, obesity, and other immunological and inflammatory diseases. It is now well-established that changes in the gut microbiome can provoke phenotypic changes in the host and promote or suppress the development of various chronic diseases. In humans and animals, imbalances in the gut microbiome have been associated with several ailments. We have shown that it is possible to effectively remodel a dysfunctional microbiome using appropriate small molecule bacterial growth modulators to treat or prevent the progression of atherosclerosis in animal models of the disease. We are seeking qualified Postdoctoral Fellows to join our multidisciplinary team of scientist and take part in various aspects of this broad research effort.

The candidate will be involved in several aspects of this project, including i) refinement and implementation of the compound screening and scoring process to identify leads, ii) identification and functional characterizations of disease-associated targets and biological pathways in the host and gut microbiota by using gut microbiota transcriptome analysis, metabolomics, and host gene expression changes, and iii) exploring the effectiveness of identified compounds in several distinct animal models of diseases. Candidates with demonstrated experience in biological research, microbiome studies, and genomics are highly desirable.

Interested applicants should send their curriculum vitae, a brief description of prior research, and contact information for references to M. Reza Ghadiri directly at

Position Description
Location: San Diego, California
Additional Information:
Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Preferred Qualifications:
Job Closing Date:
Open Until Filled Yes
Job Posting Category Postdoctoral
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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