Job Description

Requisition Number 07045
Department Name: Immunology and Microbiology - CA
Position Type: Full Time
Position Title Postdoctoral Associate
Position Summary:

Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Although current standards of care suppress HBV replication, they fail to eradicate HBV from individuals. Therefore, new strategies are absolutely required to cure HBV.

Our laboratory identified a novel and exciting therapeutic approach showing solid premises to provide such a cure. We developed a new in vivo imaging system that allows us to visualize and monitor in live the growth or death of bioluminescent HBV-human infected hepatocytes in the liver of mice.

This in live bioluminescent visualization system permitted us to identify a new adeno-associated virus gene therapy strategy that kills HBV-infected hepatocytes in mice but preserved non-infected cells. This novel therapeutic strategy exploits the viral replication machinery to induce apoptosis and cell death, thereby eliminating normally resilient HBV reservoirs.

A postdoctoral position is immediately available to further develop this in live visualization system and this HBV cure.

Position Description
Location: San Diego, California
Additional Information:
Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

Basic Qualifications:Must possess a Ph.D. A pending doctoral degree may also be considered with approval of the Principal Investigator. Please send a curriculum vitae (CV) to Dr. Philippe Gallay at

Lab website:

Preferred Qualifications:
Compensation: Salary is commensurate with experience.
Job Closing Date:
Open Until Filled Yes
Job Posting Category Postdoctoral
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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