|Department Name:||Immunology and Microbiology - CA|
|Position Type:||Full Time|
|Position Title||Postdoctoral Associate|
|Position Summary:|| |
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is the major cause of cancer death worldwide, accounting for over half a million deaths per year. The development of non-alcoholic steatohepatitis (NASH) and liver fibrosis leads to HCC. To date, there is no treatment to interrupt or treat NASH, liver fibrosis and HCC.
In collaboration with several pharmaceutical companies, our lab demonstrated that small inhibitors of the foldase family of cyclophilins (Cyp) - the cyclophilin inhibitors (CypI) - prevent the development of liver fibrosis and HCC in mouse models.
A postdoctoral position is immediately available to i) understand the mechanisms of anti-liver damage action of CypI; ii) determine which Cyp members participate in the development of NASH, liver fibrosis and HCC using CypA, CypB and CypD knockout mice recently generated in our lab; and iii) to test the therapeutic efficacy of CypI provided by pharmaceutical companies in various liver damage developed and used in our lab.
|Location:||San Diego, California|
|Physical Requirements:|| |
This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.
|Basic Qualifications:|| |
Must possess a Ph.D. A pending doctoral degree may also be considered with approval of the Principal Investigator. Please send a curriculum vitae (CV) to Dr. Philippe Gallay at firstname.lastname@example.org.
Lab website: http://www.scripps.edu/gallay
|Compensation:||Salary is commensurate with experience.|
|Job Closing Date:|
|Open Until Filled||Yes|
|Job Posting Category||Postdoctoral|
|EEO Statement|| |
The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.