|Position Description || |
Calibr, a division of Scripps Research, is seeking a talented Investigator or Principal Investigator to work within a dynamic, interdisciplinary team of scientists in developing new therapeutic approaches in oncology and immuno-oncology to unmet medical needs through early stage translational research.
|Physical Requirements: || |
Responsibilities and Duties
* Lead high risk / high reward programs in the design and development of therapeutics for novel oncology and immuno-oncology targets.
* Effectively manage the productivity of cross-functional drug discovery efforts to advance programs and institutional goals
* Responsible for establishing and executing program plans, evaluating new opportunities, and managing timelines for programs ranging from discovery to IND-enabling
* Responsible for conceiving and managing wet lab experiments
* Implement knowledge/expertise within a lab group to successfully execute major parts of a project including a complement of technical and logistical/strategic activities. Examples may include:
* Drive lead optimization of assets up to and including IND-enabling studies
* Participate in decision-making processes within the project team by actively engaging in scientific and technical discussions
* Serve as an immuno-oncology team leader across multiple programs across all a broad set of disease area
* Programs to include both biologics and small molecule modalities, with support from internal protein expression and medicinal chemistry teams.
* Communicates (both in writing and verbally) project status, issues, schedule and accomplishments to various management and stakeholder groups in an effective manner
* Proven track record of working in multi-disciplinary team setting including ability to interface with academics and in immunology, oncology chemical biology, cell biology, with knowledge of pharmacology and toxicology.
* Critically evaluates project data while rigorously driving data-driven Go/No-go decisions, including the identification of resource constraints and bottlenecks
* Promotes an overall group culture of agility, pro-action, collaboration, and innovation
* Ambition to grow into taking on future leadership roles
Directs the appropriate use of budgetary resources to support project and institute goals. Able to think in terms of global long-term project goals as well as day-to-day lab goals/activities. Develops long-term plans within constraints of project goals/timelines. Designs, executes, interprets and reports results of work independently and in collaboration with interdisciplinary team. Additionally, oversees consistency and accuracy of results and documentation. Expected to solve the majority of technical problems that arise with minimal supervisory input and to address strategic challenges in conjunction with supervisory input. Ensures escalation of issues and risks that significantly affect timelines.
Will communicate with colleagues, CRO personnel, and management teams to lead projects effectively.
SCOPE AND COMPLEXITY
Addresses problems of a variety of complexities from granular technical challenges to timeline, resource, and strategic challenges (with supervisory input). Responsible for collection of team reports, organization of project status presentations, and delivery to key stakeholders. Responsible for driving project timelines and benchmarks for success. Works within project teams to assess risks, identify key issues, and develop solutions. Activities are to be carried out efficiently in a scientifically rigorous manner.
SUPERVISION OF OTHERS
Supervision of 1-2 research assistant/associates with expectation to grow into role with greater responsibility. May have oversight of CRO to support goals and timelines on specific aspects of programs, however work will be primarily driven internally.
|Basic Qualifications: || |
* Candidates must have Ph.D. in a pertinent scientific field with >3-5 years of experience for Investigator, 5+ years for Principal Investigator
* Experience and exceptional track record in immunology and oncology are essential
* Demonstrated success in oncology or immuno-oncology programs from project inception through optimization, either in preclinical evaluation to development candidate nomination, or in the publication of work in high-impact journals
* Strong skills and a proven track record in area of cell biology.
* Propose new project ideas and enable resources to execute on a portfolio of programs
* Highly motivated, creative, and devoted to project goals
* Impeccable attention to detail, and excellent ability to perform hands on experiments, research, design, and organize project designs and maintain detailed documentation
* Able to contribute in a meaningful way to scientific discourse
* Possess effective verbal, written, and interpersonal communication skills
* Ability to navigate and be successful in a fast-paced, highly matrixed work environment
* Able to provide leadership on a cross-functional team
* Self-motivated, ability to exercise sound judgment and operate with a high degree of independence regarding routine and non-routine assignments
* Strong attention to detail, organizational skills and the ability to manage multiple tasks
|EEO Statement || |
The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.