Job Description

Requisition Number 06926
Department Name: Pharmacology - Joseph
Position Type: Full Time
Position Title Research Assistant II - Bioanalytical
Position Summary:

Calibr, a division of Scripps Research, is focused on innovative early stage translational research in collaboration with academic partners in the areas of regenerative medicine, cancer biology, cardiovascular and metabolic disease, immunology and infectious disease. ?
Position Overview:
We are seeking a highly motivated Research Assistant in the DMPK group to join Calibr’s multi-disciplinary drug discovery efforts. The DMPK Research Assistant will serve a multi-faceted role as (1) DMPK bioanalytical associate for early discovery programs and (2) manager of external workflows to ensure high quality data. The role includes collaboration with CROs as well as reviewing data and summary reports generated externally. The successful candidate will be an accomplished "do-er" who has significant interest in applying state-of-the-art technologies for bioanalysis, drug metabolism, drug transport and pharmacokinetics.

The DMPK department works in close partnership with disciplines such as medicinal chemistry, in vivo pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize lead compounds, select clinical candidates, conduct preclinical studies, support clinical development and contribute to regulatory filings

Essential Duties and Responsibilities:
* Assists in the validation and implementation of LC-MS/MS assays for analysis of non-clinical pharmacokinetic or toxicokinetic samples.
* Perform bioanalytical testing and reporting of study samples.
* Assists in the preparation and validation of bioanalytical reports from internal sources and from CROs.
* Assists in troubleshooting assays.
* Maintenance of accurate and detailed scientific notebooks.
* Works relatively independently to meet short term goals and objectives.
* Operate and maintain LC-MS equipment.

Position Description

Calibr, a division of Scripps Research, is focused on innovative early stage translational research in collaboration with academic partners in the areas of regenerative medicine, cancer biology, cardiovascular and metabolic disease, immunology and infectious disease. ?
Position Overview:
We are seeking a highly motivated Research Assistant in the DMPK group to join Calibr’s multi-disciplinary drug discovery efforts. The DMPK Research Assistant will serve a multi-faceted role as (1) DMPK bioanalytical associate for early discovery programs and (2) manager of external workflows to ensure high quality data. The role includes collaboration with CROs as well as reviewing data and summary reports generated externally. The successful candidate will be an accomplished "do-er" who has significant interest in applying state-of-the-art technologies for bioanalysis, drug metabolism, drug transport and pharmacokinetics.

The DMPK department works in close partnership with disciplines such as medicinal chemistry, in vivo pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize lead compounds, select clinical candidates, conduct preclinical studies, support clinical development and contribute to regulatory filings

Essential Duties and Responsibilities:
* Assists in the validation and implementation of LC-MS/MS assays for analysis of non-clinical pharmacokinetic or toxicokinetic samples.
* Perform bioanalytical testing and reporting of study samples.
* Assists in the preparation and validation of bioanalytical reports from internal sources and from CROs.
* Assists in troubleshooting assays.
* Maintenance of accurate and detailed scientific notebooks.
* Works relatively independently to meet short term goals and objectives.
* Operate and maintain LC-MS equipment.

Location: California
Additional Information:
Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

* BS or MS degree in chemistry, biochemistry or related scientific discipline with 1-3 years of experience, preferably in a bioanalytical laboratory.
* Prior experience running HPLC or LC-MS instrumentation.
* Strong attention to details, critical thinking, and good trouble-shooting skills are required
* Ability to manage multiple competing priorities, while working on multiple projects simultaneously
* Excellent communication skills as well as a demonstrated ability to work in a fast-paced environment.
* Proficiency with spreadsheet, word processing, and graphical computer programs (MS EXCEL, MS WORD, GraphPad Prism, for example) required
* Good organizational, documentation and technical writing skills required

Preferred Qualifications:
Compensation: DOE
Job Closing Date:
Open Until Filled Yes
Job Posting Category Scientific & Technical
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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