Job Description

Requisition Number 07557
Department Name: Biology - Laborda
Position Type: Full Time
Position Title Research Assistant III
Position Summary:

The California Institute for Biomedical Research (Calibr) is seeking talented Research Associate candidates in the area of cell biology, interdisciplinary team of scientists focused on early stage translational research.
This position will work as part of a small team of interdisciplinary scientists to translate novel cell and protein therapies for the treatment of cancer into first in human clinical trials. Specifically, projects will be focused in the development of CAR-T cell and bispecific antibody platforms. While working within the scope of these projects this position will also have the unique opportunity to be exposed to a wide range of other projects at Calibr covering infectious and neglected tropical diseases, metabolic disorders, autoimmunity, and others. Calibr’s open lab space design and collaborative environment encourages the seamless flow of ideas within and between research groups.

Position Description

Plan and conduct complex or novel research projects that involve the performance of non-routine procedures, development of new or improved techniques and evaluation criteria, thorough data analysis and complex interpretations of results; assist in designing experiments; operate sophisticated scientific lab equipment; may plan and conduct a small or average size project or a large portion of a more diverse project; may supervise or provide work direction and training to a small staff of professional-level employees; perform other related duties, tasks and responsibilities as required or assigned.  

Location: San Diego, California
Additional Information:
Physical Requirements:

Details of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

Requires a Bachelor’s degree in a relevant scientific discipline or an equivalent combination of education, training and/or experience from which comparable knowledge, skill and abilities have been attained. Requires a minimum of 5 years experience. Candidates possessing a Master’s degree, 3+ years experience required.
* Excellent ability to perform hands on experiments, attention to detail, research, design, and organize project designs and maintain detailed documentation.
* Highly motivated, creative, and devoted to project goals.
* Able to collaborate proficiently and communicate effectively with colleagues and management teams.
* Able to contribute in a meaningful way to scientific discourse.
* A strong background in cell culture is essential. The candidate must have experience working with primary human immune cells and culturing multiple cell lines including, but not limited to, common tumor cell lines used in immuno-oncology research..
* Experience and knowledge of the immune system is a plus. The candidate must show a fundamental understanding of the immune system. Experience in T cell biology,tumor immunology, as well as other immune components is preferred,
* Hands-on experience with in vitro assays commonly used in immuno-oncology is important. Experience assessing the activity of immune cells in vitro using cytotoxicity, proliferation, activation, viability and survival assays is preferred.
* Experience preparing reagents for in vivo assays as well as collection (blood, liver, spleen, tumor), processing, and analysis of samples from in vivo experiments is important.
* Experience with multi-color flow cytometry is a plus. The candidate mayhave experience with multi-color flow cytometry and flow data analysis
* Experience with cell transfection and transduction systems is preferred. The candidate will be required to generate high quality lentivirus for the transduction of both primary immune cells and stablished cell lines.
* Experience with molecular biology techniques is preferred. Experiments include but not limited to molecular cloning, DNA preparation, protein expression/purification, immunoprecipitation, Western blots, etc.
* Experience using Prism, FlowJo, and Office software is important.

Preferred Qualifications:
Compensation: DOE
Job Closing Date:
Open Until Filled Yes
Job Posting Category Scientific & Technical
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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