Job Description

Requisition Number 07469
Department Name: Molecular Medicine - CA
Position Type: Full Time
Position Title Staff Scientist, Sr. Biomedical Informatics
Position Summary:

The Senior Staff Scientist, Biomedical Informatics will report to Associate Professor and Director of Genomics at The Scripps Research Translational Institute (SRTI) at Scripps Research to provide practical, creative, and comprehensive solutions to cutting edge problems in combining phenotypic data with human genetics and genomics data at large scale. This role will work with a small team of computational and quantitative biologists on human genomics projects primarily focused on the detection of novel genetic associations, prediction of disease risk from genetic and phenotypic data, and the use of genetic information in precision medicine initiatives.
RESPONSIBILITIES AND DUTIES
* Drive the design and development of complex analytical pipelines for a wide range of human datasets, including (but not limited to) electronic health records, cohort and clinical trial data, and wearable health sensor data.
* Establish, maintain, and analyze large databases of clinical and patient-generated health data as part of on-going and future research efforts.
* Independently develop new algorithms, techniques, and computational statistical methodologies to analyze datasets.
* Work collaboratively with a diverse and interdisciplinary team of physicians, computer scientists, behaviorists, and biostatisticians to address pressing biomedical questions and needs.
* Develop and maintain computational infrastructure to support analytical needs.
* Generate reports and visualizations to communicate findings to a wide audience.
* Contribute to the development of new research efforts, studies, grants, and publications.
* Perform other related duties as required or assigned.
DECISION MAKING
This is a developmental position. Reports to an SRTI or Scripps Research PI, making decisions with guidance that allows for some independent creativity and problem solving. Errors will be handled at the PI’s discretion.
COMMUNICATION
Senior Staff Scientist, Biomedical Informatics will be a key member of the Directors clinical-translational research team. Will present research proposals and results on a regular schedule within the PI’s research group and, where applicable, to project groups that include researchers from collaborating universities and companies.
SCOPE AND COMPLEXITY
Demonstrates technical proficiency, scientific creativity, and independent thought in methods of analysis and interpretation of results.
SUPERVISION OF OTHERS
This position does not supervise others.

Position Description
Location: San Diego, California
Additional Information:

The Senior Staff Scientist, Biomedical Informatics will report to Associate Professor and Director of Genomics at The Scripps Research Translational Institute (SRTI) at Scripps Research to provide practical, creative, and comprehensive solutions to cutting edge problems in combining phenotypic data with human genetics and genomics data at large scale. This role will work with a small team of computational and quantitative biologists on human genomics projects primarily focused on the detection of novel genetic associations, prediction of disease risk from genetic and phenotypic data, and the use of genetic information in precision medicine initiatives.

Physical Requirements:

This position works in a laboratory or vivarium environment. Further details of the physical requirements of established essential functions for this position will be addressed/discussed during the interview process.

Basic Qualifications:

* PhD in biomedical informatics, data science, epidemiology, or related field.
* Minimum 4 years bioinformatics, software development, or related experience, preferably in a high performance computing setting.
* Solid understanding of various phenotype coding standards required, including human phenotype ontology, billing codes, with direct experience with electronic health record data preferred.
* Experience with genomics software packages, BWA, GATK, PLINK, or related packages is required.
* Strong knowledge of and experience with at least one and preferably multiple programming languages, such as (but not limited to) Python, Java, C/C++, Ruby, and JavaScript.
* Knowledge of and experience with one or more statistical programming environments or libraries, such as (but not limited to) R, pandas, and SAS is required.
* Experience with architecture and tools for managing large datasets - especially large-scale health data is preferred.
* Experience developing scalable system architectures that adhere to good software engineering principles is a major plus.
* Ability to tackle large, open-ended research questions independently and as part of a team.
* Ability to effectively prioritize workload and multi-task.
* Excellent communication, analytical and organizational skills, both written and verbal. Ability to clearly convey methods and results to provide information to scientific investigators from which researchers can draw conclusions.

Preferred Qualifications:
Compensation: Salary is commensurate with experience.
Job Closing Date:
Open Until Filled Yes
Job Posting Category Scientific & Technical
EEO Statement

The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

Application Instructions

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